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46 public companies · 46 exchange-listed
46
Total Companies
46
Exchange Listed
26
Filed 10-K
12
States Represented
Total Sector Revenue
$4.74B
Aggregate of 23 companies with XBRL data
Avg Net Margin
-50.4%
Intensely competitive· Based on 23 filings
Sector Analysis · Sprytne.com
As of April 2026, the Medicinal Chemicals & Botanical Products sector (SIC 2833) reports a combined revenue of $4.74B across 23 SEC-tracked entities. With an average net margin of -50.4%, this industry is classified as loss-making on average. Trulieve Cannabis Corp. leads the sector with $1.18B in reported revenue. The data is derived exclusively from official SEC EDGAR XBRL submissions and reflects the most recently filed 10-K annual reports.
Data aggregated from SEC EDGAR XBRL submissions · Updated March 2026
| Rank | Company | Revenue | Net Income | Net Margin | vs Industry Avg |
|---|---|---|---|---|---|
| #1 | Trulieve Cannabis Corp.TCNNF | $1.18B | $-252,727,000 | -21.4% | +29.0pp |
| #2 | USANA HEALTH SCIENCES INCUSNA | $925.3M | $10.8M | 1.2% | +51.5pp |
| #3 | Tilray Brands, Inc.TLRY | $821.3M | $-2,186,738,000 | -266.3% | -215.9pp |
| #4 | Ascend Wellness Holdings, Inc.AAWH | $500.6M | $-80,899,000 | -16.2% | +34.2pp |
| #5 | Jushi Holdings Inc.JUSHF | $257.5M | $-48,777,000 | -18.9% | +31.4pp |
| Industry Average | $206.2M | $-110,962,439.348 | -50.4% | baseline | |
Adia Nutrition, Inc.
CIK: 0001160420 · NV
AIBOTICS, INC.
CIK: 0001763329 · NV · 10-K: 2025-04-11
AKANDA CORP.
CIK: 0001888014 · A6
Ascend Wellness Holdings, Inc.
CIK: 0001756390 · DE · 10-K: 2026-03-12
AURORA CANNABIS INC
CIK: 0001683541 · A1
Ayr Wellness Inc.
CIK: 0001847462 · A1
biote Corp.
CIK: 0001819253 · · 10-K: 2026-03-13
Bon Natural Life Ltd
CIK: 0001816815 · E9
C21 Investments Inc.
CIK: 0000831609 · A1
Cannaisseur Group Inc.
CIK: 0001879270 · DE · 10-K: 2026-03-23
Canopy Growth Corp
CIK: 0001737927 · Z4 · 10-K: 2025-05-30
CBD Life Sciences Inc.
CIK: 0001776073 · NV
Charlie's Holdings, Inc.
CIK: 0001134765 · NV · 10-K: 2025-05-29
China Foods Holdings Ltd.
CIK: 0001310630 · DE · 10-K: 2025-04-14
Cordyceps Sunshine Biotech Holdings Co., Ltd.
CIK: 0001885680 ·
Cresco Labs Inc.
CIK: 0001832928 · A1
Cronos Group Inc.
CIK: 0001656472 · A1 · 10-K: 2026-02-26
Curaleaf Holdings, Inc.
CIK: 0001756770 · A1
CYANOTECH CORP
CIK: 0000768408 · NV · 10-K: 2025-06-20
Definium Therapeutics, Inc.
CIK: 0001813814 · A1 · 10-K: 2026-02-26
FARLONG HOLDING Corp
CIK: 0002054964 ·
FITLIFE BRANDS, INC.
CIK: 0001374328 · NV · 10-K: 2025-03-27
Functional Brands Inc.
CIK: 0001837254 · DE
Glass House Brands Inc.
CIK: 0001848731 · A1
Glucose Health, Inc.
CIK: 0001420108 · DE · 10-K: 2017-03-29
HEALTHY EXTRACTS INC.
CIK: 0001630176 · NV · 10-K: 2025-04-01
IM Cannabis Corp.
CIK: 0001792030 · A1
Jushi Holdings Inc.
CIK: 0001909747 · A1 · 10-K: 2025-03-06
Leef Brands Inc.
CIK: 0001711141 · A1
MANNATECH INC
CIK: 0001056358 · TX · 10-K: 2025-03-26
MARIMED INC.
CIK: 0001522767 · DE · 10-K: 2026-03-12
Medikra Inc.
CIK: 0002078035 · E9
MediWound Ltd.
CIK: 0001593984 · L3
NATURAL ALTERNATIVES INTERNATIONAL INC
CIK: 0000787253 · DE · 10-K: 2025-09-23
NEUTRA CORP.
CIK: 0001512886 · WY · 10-K: 2024-08-02
Niagen Bioscience, Inc.
CIK: 0001386570 · DE · 10-K: 2026-03-04
NYB Holdings Ltd
CIK: 0002100835 · E9
PANACEA LIFE SCIENCES HOLDINGS, INC.
CIK: 0001552189 · NV · 10-K: 2024-04-01
Raphael Pharmaceutical Inc.
CIK: 0001415397 · NV · 10-K: 2025-03-31
Regencell Bioscience Holdings Ltd
CIK: 0001829667 · E9
SNDL Inc.
CIK: 0001766600 · A0
Synergy CHC Corp.
CIK: 0001562733 · NV · 10-K: 2025-03-31
Target Group Inc.
CIK: 0001586554 · DE · 10-K: 2025-03-27
Tilray Brands, Inc.
CIK: 0001731348 · · 10-K: 2025-07-29
Trulieve Cannabis Corp.
CIK: 0001754195 · A1 · 10-K: 2026-02-26
USANA HEALTH SCIENCES INC
CIK: 0000896264 · UT · 10-K: 2026-03-16