BIOGEN INC.

PURCHASE OF FMD VAC FROM BIOGENESIS BAGO S.A. ORDER SPECIFICS SUCH AS ANTIGENS AND QUANTITY ORDERED ARE FOR OFFICIAL USE ONLY (FOUO)

UTILIZING THE CONTRACTORS TECHNOLOGY, HUMAN INDUCED PLURIPOTENT STEM CELLS WILL UNDERGO DIFFERENTIATION TO PRE-MEGAKARYOCYTES (PREMK+), WHICH ARE STOCKPILED THROUGH CRYOPRESERVATION. FROZEN PREMK+ ARE THAWED AND FURTHER DIFFERENTIATED TO MATURE MEGAK

FY23 FMD VAC FOR NAVVCB FROM BIOGENESIS BAGO

FY21 NAVVCB FMD VAC ORDER FROM BIOGENESIS BAGO S.A.

BG - NAVVCB PURCHASE BIOGENESIS NAVVCB FMD VAC AND RELATED ITEMS

IGF::OT::IGF PROTOTYPE MONITORING, REPORTING AND VERIFICATION SYSTEM FOR THE REGIONAL SCALE: THE BOSTON-DC CORRIDOR. THE WORLD S POPULATION GROWTH IS INCREASINGLY CONCENTRATED IN URBAN AREAS AND THIS TREND IS EXPECTED TO CONTINUE IN THE FUTURE. URBANIZATION HAS A PROFOUND IMPACT ON CARBON DYNAMICS, LEADING TO INCREASES IN ANTHROPOGENIC CARBON DIOXIDE (CO2) EMISSIONS AND DECREASES IN BIOGENIC FLUXES FROM THESE AREAS. THE LATTER ARE A KEY COMPONENT OF A CARBON MONITORING SYSTEM (CMS), WHILE SPATIALLY AND TEMPORALLY RESOLVED ESTIMATES OF ANTHROPOGENIC FLUXES ARE CENTRAL TO MEETING GREENHOUSE GAS EMISSIONS REDUCTIONS GOALS. WE INTEND TO DESIGN A MEASUREMENT NETWORK AND DEVELOP AN ACCOMPANYING ATMOSPHERIC MODELING FRAMEWORK FOR DOWNSCALING THE CURRENT NASA CMS FLUX PRODUCTS TO THE REGIONAL AND LOCAL SCALES PERTINENT TO MONITORING, REPORTING, AND VERIFICATION (MRV). OUR PROPOSED RESEARCH WILL FOCUS ON THE BOSTON-DC MEGALOPOLIS CORRIDOR, WHERE ABOUT 17% OF THE U.S. POPULATION LIVES ON LESS THAN 2% OF THE NATION S LAND AREA, MAKING IT A KEY SOURCE OF US ANTHROPOGENIC CO2 EMISSIONS. SIMULTANEOUSLY, THESE URBAN AREAS ARE INTERSPERSED WITH VEGETATION THAT IMPOSES A STRONG BIOGENIC SIGNAL ON THE ATMOSPHERIC CO2 MIXING RATIOS. THE PROPOSED RESEARCH WILL PROCEED ALONG THREE MAIN LINES: 1) HIGH-RESOLUTION TRANSPORT MODELING (WRF-STILT) CUSTOMIZED AND VERIFIED FOR THE REGION, 2) HIGH-RESOLUTION CO2 FLUX MODEL INCORPORATING ANTHROPOGENIC EMISSIONS ESTIMATES AND THE CASA MODEL (INCLUDING ITS 0.5-DEG RESOLUTION VARIANT THAT PROVIDES THE FOUNDATIONAL BIOSPHERE MODEL FOR THE CURRENT CMS FLUX PRODUCT AND NESTED HIGHER RESOLUTION RUNS TO REPRESENT THE SCALE SENSITIVITY WITHIN HETEROGENEOUS URBAN AREAS), AND 3) INVERSE CO2 FLUX ESTIMATES CORRESPONDING TO IN-SITU AND REMOTE CO2 OBSERVATIONS IN AND AROUND BOSTON, NEW YORK CITY, AND WASHINGTON DC. AS PART OF THE PROPOSED WORK, WE WILL QUANTIFY ERRORS IN THE WRF-STILT SIMULATIONS OF THE PLANETARY BOUNDARY LAYER (PBL), RELYING FOR THIS PURPOSE ON REMOTELY SENSED PBL MEASUREMENTS BY THE SIGMA SPACE CORPORATION S MICRO PULSE LIDAR (MPL). THE PBL HEIGHT IS A KEY PARAMETER ENTERING INVERSE FLUX ESTIMATES, AS IT DETERMINES THE MIXING REGION AND VARIES INVERSELY TO THE TRACE GAS CONCENTRATIONS. A KEY RESULT OF THE PROPOSED RESEARCH WILL BE THE QUANTIFICATION OF OBSERVING REQUIREMENTS FOR FLUX UNCERTAINTY REDUCTION TO LEVELS NEEDED FOR MRV. OUR PROPOSAL ADDRESSES TWO STATED GOALS OF THE NNH13ZDA001N-CMS SOLICITATION: STUDIES USING COMMERCIAL OFF-THE-SHELF TECHNOLOGIES TO PRODUCE AND EVALUATE PROTOTYPE MRV SYSTEM APPROACHES AND STUDIES TO IMPROVE THE CHARACTERIZATION AND QUANTIFICATION OF ERRORS AND UNCERTAINTIES IN EXISTING AND/OR PROPOSED NASA CMS PRODUCTS, INCLUDING ERRORS AND UNCERTAINTIES IN THE ALGORITHMS, MODELS, AND ASSOCIATED METHODOLOGIES UTILIZED IN CREATING THEM. THE PROPOSED WORK WILL LEVERAGE AND EXTEND THE CURRENT CMS PROJECTS LED BY DRS. ARLYN ANDREWS AND STEVEN PAWSON, WITH WHICH THE LEAD PROPOSING TEAM AT ATMOSPHERIC AND ENVIRONMENTAL RESEARCH (AER) IS INTIMATELY INVOLVED, AND THE CMS PILOT SURFACE CARBON FLUXES MODELING ANALYSIS.

FY21 NAFMDVB ORDER FOR VAC FORM BG

BG - NAFMDVB PURCHASE BIOGENESIS BAGO S.A. CONTRACT #: 12639520D0055 QTY 2.5M DOSES C3 INDAIAL @.415/DOSE $1,037,500.

FY22 NAVVCB FMD VAC ORDER FROM BIOGENESIS BAGO S.A.

NEW TASK ORDER: ACCOUNTING FRAMEWORK FOR GHG EMISSIONS FROM BIOENERGY AND OTHER BIOGENIC SOURCES".