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1,281 public schools in South Carolina. Showing top 100 by enrollment. Data from the NCES (National Center for Education Statistics).
| # | School | City | Students | S/T Ratio |
|---|---|---|---|---|
| 1 | SC Connections Academy | Columbia | 5,955 | 23.4:1 |
| 2 | Dorman High | Roebuck | 3,925 | 18:1 |
| 3 | Cyber Academy of South Carolina | Greenville | 3,493 | 21.6:1 |
| 4 | Summerville High | Summerville | 3,293 | 20.7:1 |
| 5 | Carolina Forest High | Myrtle Beach | 3,181 | 19.5:1 |
| 6 | Boiling Springs High | Boiling Springs | 2,796 | 18.5:1 |
| 7 | Ashley Ridge High | Summerville | 2,735 | 20.3:1 |
| 8 | Stratford High | Goose Creek | 2,710 | 16.4:1 |
| 9 | Clover High | Clover | 2,698 | 15.2:1 |
| 10 | Wando High | Mount Pleasant | 2,593 | 18.3:1 |
| 11 | Cane Bay High | Summerville | 2,490 | 18.3:1 |
| 12 | Lexington High | Lexington | 2,475 | 15.2:1 |
| 13 | South Carolina Virtual Charter School | West Columbia | 2,350 | 18.1:1 |
| 14 | James F. Byrnes High | Duncan | 2,315 | 18.8:1 |
| 15 | Spring Valley High | Columbia | 2,314 | 18.8:1 |
| 16 | Fort Dorchester High | North Charleston | 2,301 | 16.8:1 |
| 17 | Mauldin High | Mauldin | 2,274 | 19.6:1 |
| 18 | Sumter High School | Sumter | 2,214 | 18:1 |
| 19 | Spartanburg High | Spartanburg | 2,205 | 16.1:1 |
| 20 | River Bluff High | Lexington | 2,160 | 15.5:1 |
| 21 | Woodmont High | Piedmont | 2,157 | 18.9:1 |
| 22 | Blythewood High | Blythewood | 2,117 | 14.9:1 |
| 23 | Hillcrest High | Simpsonville | 2,085 | 19.9:1 |
| 24 | J. L. Mann High Academy | Greenville | 2,062 | 18.2:1 |
| 25 | West Ashley High | Charleston | 2,043 | 16.9:1 |
| 26 | Fort Mill High | Fort Mill | 2,041 | 15.1:1 |
| 27 | White Knoll High | Lexington | 2,031 | 14.5:1 |
| 28 | RB Stall High | North Charleston | 2,025 | 16.9:1 |
| 29 | Goose Creek High | Goose Creek | 2,002 | 17.9:1 |
| 30 | Rock Hill High | Rock Hill | 1,998 | 16.9:1 |
| 31 | T. L. Hanna High | Anderson | 1,994 | 19.4:1 |
| 32 | Berkeley High | Moncks Corner | 1,943 | 19.8:1 |
| 33 | Easley High | Easley | 1,885 | 19:1 |
| 34 | St. James High | Murrells Inlet | 1,880 | 17.7:1 |
| 35 | West Florence High | Florence | 1,879 | 18.6:1 |
| 36 | Gaffney High | Gaffney | 1,878 | 17.6:1 |
| 37 | Nation Ford High | Fort Mill | 1,871 | 13.9:1 |
| 38 | Indian Land High | Lancaster | 1,821 | 18.2:1 |
| 39 | Riverside High | Greer | 1,816 | 19.5:1 |
| 40 | Greenville Senior High Academy | Greenville | 1,791 | 19.5:1 |
| 41 | Wade Hampton High | Greenville | 1,780 | 18.7:1 |
| 42 | Lugoff-Elgin High | Lugoff | 1,773 | 18.9:1 |
| 43 | Northwestern High | Rock Hill | 1,764 | 16.6:1 |
| 44 | Lucy Garrett Beckham High | Mt. Pleasant | 1,763 | 17.5:1 |
| 45 | Greenwood High | Greenwood | 1,751 | 18.6:1 |
| 46 | American Leadership Academy South Carolina-Lexington Campu | Lexington | 1,728 | 12.6:1 |
| 47 | Westside High | Anderson | 1,714 | 17.3:1 |
| 48 | Socastee High | Myrtle Beach | 1,712 | 17.6:1 |
| 49 | Conway High | Conway | 1,711 | 18:1 |
| 50 | Dutch Fork High | Irmo | 1,705 | 14.6:1 |
| 51 | North Augusta High | North Augusta | 1,697 | 18.9:1 |
| 52 | Ridge View High | Columbia | 1,696 | 17.5:1 |
| 53 | Westwood High | Blythewood | 1,689 | 17.6:1 |
| 54 | York Preparatory Academy | Rock Hill | 1,681 | 15.1:1 |
| 55 | May River High | Bluffton | 1,665 | 15.3:1 |
| 56 | North Myrtle Beach High | Little River | 1,654 | 17.8:1 |
| 57 | Catawba Ridge High School | Fort Mill | 1,651 | 16.3:1 |
| 58 | Ruldolph G. Gordon School at Jones Mill | Simpsonville | 1,639 | 16.1:1 |
| 59 | Chapin High | Chapin | 1,630 | 15.1:1 |
| 60 | South Florence High | Florence | 1,627 | 16.3:1 |
| 61 | James Island Charter High | Charleston | 1,597 | 14.9:1 |
| 62 | Myrtle Beach High | Myrtle Beach | 1,595 | 17.9:1 |
| 63 | Legacy Early College | Greenville | 1,583 | 13.4:1 |
| 64 | Laurens District 55 High | Laurens | 1,540 | 13.1:1 |
| 65 | Eastside High | Taylors | 1,528 | 19.6:1 |
| 66 | York Comprehensive High | York | 1,525 | 17.5:1 |
| 67 | Midland Valley High | Graniteville | 1,486 | 17.5:1 |
| 68 | Cane Bay Middle | Summerville | 1,475 | 17.2:1 |
| 69 | River Oaks Elementary | Myrtle Beach | 1,415 | 16.5:1 |
| 70 | Greer High | Greer | 1,413 | 17.7:1 |
| 71 | Colleton County High | Walterboro | 1,396 | 17.2:1 |
| 72 | Lancaster High | Lancaster | 1,393 | 17:1 |
| 73 | Bluffton High | Bluffton | 1,384 | 14.1:1 |
| 74 | Bridges Preparatory School | Beaufort | 1,355 | 15.4:1 |
| 75 | Berkeley Middle | Moncks Corner | 1,345 | 21.3:1 |
| 76 | Airport High | West Columbia | 1,338 | 18.6:1 |
| 77 | A. C. Flora High | Columbia | 1,334 | 16.5:1 |
| 78 | Richard H. Gettys Middle | Easley | 1,321 | 17.2:1 |
| 79 | North Myrtle Beach Middle | Little River | 1,321 | 16.1:1 |
| 80 | Hilton Head Island High | Hilton Head Island | 1,317 | 13.2:1 |
| 81 | Wilson High | Florence | 1,316 | 15:1 |
| 82 | Horse Creek Academy | Aiken | 1,308 | 12.7:1 |
| 83 | Lower Richland High | Hopkins | 1,306 | 15.5:1 |
| 84 | Carolina Forest Elementary | Myrtle Beach | 1,306 | 16.3:1 |
| 85 | South Aiken High | Aiken | 1,305 | 16.3:1 |
| 86 | Travelers Rest High | Travelers Rest | 1,303 | 18.4:1 |
| 87 | Richland Northeast High | Columbia | 1,301 | 13:1 |
| 88 | Woodland Elementary | Greer | 1,298 | 17.1:1 |
| 89 | Berea High | Greenville | 1,296 | 18.5:1 |
| 90 | Muller Road Middle | Blythewood | 1,289 | 15.7:1 |
| 91 | E. L. Wright Middle | Columbia | 1,285 | 15.1:1 |
| 92 | Pickens High | Pickens | 1,281 | 16.2:1 |
| 93 | Ten Oaks Middle | Myrtle Beach | 1,270 | 16.7:1 |
| 94 | Irmo High | Columbia | 1,268 | 12.2:1 |
| 95 | Wren High | Piedmont | 1,264 | 19.2:1 |
| 96 | Aiken High | Aiken | 1,254 | 16.5:1 |
| 97 | High Point Academy | Spartanburg | 1,250 | 13.6:1 |
| 98 | Sand Hill Elementary | Summerville | 1,241 | 18.3:1 |
| 99 | C. E. Williams Middle School for Creative and Scientific Art | Charleston | 1,241 | 14.3:1 |
| 100 | Cane Bay Elementary | Summerville | 1,226 | 16.8:1 |
Data sourced from the NCES. Updated annually.